US Services

State-of-the-Art Facilities

Bridge conducts GLP-compliant preclinical studies of all types, sizes and degrees of complexity at its state-of-the-art Gaithersburg, Maryland location. The facilities — which incorporate 90,000 square feet of laboratory and support space, including 83 animal rooms and recently upgraded caging for all species — are AAALAC-accredited and USDA-registered, with OLAW assurance and both DEA and radiation licenses. Our updated vivariums for small and large animals include technologically advanced teratology, neurobehavioral, and surgery suites. And data is collected online using the Provantis^TM automated data collection system.

 

Every effort is made to ensure the ongoing environmental integrity of the Maryland facilities. Temperature, humidity, lighting and watering for animals are all continuously monitored under computer control to comply with all relevant regulatory requirements. The HVAC system provides HEPA-filtered air and maintains room air changes in accordance with the Guide for the Care and Use of Laboratory Animals. In addition, the facilities are equipped with back-up emergency generators to supply electrical power in the event of a power outage.

 

The physical security of the facilities is also an area of major concern. Extensive use is made of key cards, security cameras and background checks to limit access to authorized personnel.

Superior Services, Proven in Hundreds of Studies

Bridge Laboratories has successfully conducted over 1600 safety assessment studies (over 700 of them GLP-based) at its Maryland facilities in meeting its clients' drug development needs. These have included both short- and long-term research efforts, ranging in duration from less than 1 week to 52 weeks or longer, that have utilized our full range of preclinical research services:

• General Toxicology — focusing on carcinogenicity and acute, subchronic and chronic toxicity

• Safety Pharmacology — testing cardiovascular, respiratory, renal/urinary, gastrointestinal and central nervous systems

• DART — ranging from fertility and embryo-fetal development to neurotoxicity and neonatal dosing studies

• Vaccines — dealing with all types of vaccines in the full range of studies

Fully Accredited US and China Facilities

Bridge is one of the first preclinical CROs to offer its clients a choice of US- or China-based drug development services. Both our 90,000 square-foot Gaithersburg, Maryland and 84,000 square-foot Beijing, China sites are globally integrated:

• Equivalent SOPs – English only

• Use of Provantis^TM data acquisition software

• Integrated program management

• US board-certified toxicologists and pathologists

• Global accreditations – GLP-compliant and AAALAC-accredited (both the US and China); in addition, the US is USDA-registered with OLAW assurance and DEA and radiation licenses.

• Animal welfare procedures

• Strict confidentiality and data security

• The industry’s top staff technical training and certification program

All studies carried out at the Maryland location are supported by the very latest onsite clinical pathology evaluation tools and technology — for hematology, clinical chemistry, coagulation and urinalysis. These onsite capabilities greatly facilitate ongoing research, speed data analysis and help insure timely project completion.